Tong Li completed her doctorate at the Institute of Materials at the University of Oxford in 2011. There she worked as a postdoctoral researcher for a year after graduating. She then moved to the Australian Center for Microscopy and Microanalysis at the University of Sydney, where she conducted research from 2013 to 2015. Tong Li also spent the following year in Australia at the University of Queensland, from where she came to Germany, initially for a year as an Alexander von Humboldt Research Fellow at the Max Planck Institute for Iron Research in Düsseldorf. From 2017 to 2020, Tong Li was a junior professor at the Chair of Materials Discovery and Interfaces at Ruhr University Bochum. In the year 2020, she started her independent group Atomic-Scale Characterisation at Ruhr University Bochum.